Fantastic Beasts and Where to Find Them – Original Motion Picture Soundtrack av James Newton Howard är musiken till den första filmen i Wizarding World-spinoffen, utgivet 18 november 2016 på 2xCD. Howard skapar ett magiskt score som följer Newt Scamander och hans magiska varelser genom 1920-talets New York, med teman för Niffler, Thunderbird, Demiguise och Obscurus.

Formatet är 2xCD.

CD 1:

1. Main Titles – Fantastic Beasts and Where to Find Them
2. There Are Witches Among Us / The Ankh, the Niffler
3. Tina Takes Newt In / MACUSA Headquarters
4. Pie or Strudel / Escaping Queenie and Tina's Place
5. Credence Hands Out Leaflets
6. Inside the Case
7. The Erumpent
8. In the Cells
9. Tina and Newt Trial / Let's Get the Good Stuff Out / You're One of Us Now / Swooping Evil
10. Gnarlak Negotiations
11. The Demiguise and the Occamy
12. A Close Friend
13. The Obscurus / Rooftop Chase
14. He's Listening to You, Tina
15. Relieve Him of His Wand / Newt Releases the Thunderbird / Jacob's Farewell
16. Newt Says Goodbye to Tina / Jacob's Bakery
17. End Titles – Fantastic Beasts and Where to Find Them

CD 2 (Bonus Tracks):

1. A Man and His Beasts
2. Soup and Leaflets
3. Billywig
4. The Demiguise and the Lollipop
5. I'm Not Your Ma
6. Blind Pig
7. Newt Talks to Credence
8. End Titles (Pt. 2) – Fantastic Beasts and Where to Find Them
9. Kowalski Rag